I have tried Ketotifen in order to deal with the unusual sinus headaches, nasal congestion, and post-nasal drip (possibly EDS/mast cells related) I am suffering from.
I have taken it for 2 days now. Each day, I took two doses, one in the morning, one before bedtime. Each dose was 0.5 mg. The drug seems to help me A LOT.
However, I have been experiencing a significant side effect: extreme sleepiness. During the two days that I’ve been taking the drug, I have slept around 18 hours per day. I feel very sleepy, and slightly dizzy.
Has anyone else experienced this? Is this side effect transient (i.e. will it go away after some initial period), or is it more permanent?
Also, has anyone tried desloratadine as a treatment of “wild” mast cells, and to regulate histamines? It seems like it may also have a stabilizing effect on mast cells: http://www.ncbi.nlm.nih.gov/pubmed/15575942 .