Lots of interesting stuff here. I DO think we tend to be acidic (is it due to chronic inflammation? I don’t know). Many of us on Diamox have to avoid acidity and it can be a beast to get on top of for many of us! I agree with Lab-Scientist-Lady that your symptoms do sound a lot like the beginnings of interstitial cystitis, and acidity HURTS when your bladder is damaged. Alkaline drops are GREAT! Sodium bicarb is often necessary, but you may want to have a urologist or nephrologist monitor you because it can increase your risk of kidney stones. Gluten sensitivity can mimic ALS, MS, etc. Many of us try to avoid inflammation, and gluten is one of the first things to go. I say this as I’m staring at a delicious homemade, warm, cream-cheese danish that my mother-in-law just brought over! Agh!