I can so relate to your notes about hormone involvement. I have poly cystic ovary syndrome with my EDS and type II diabetes. When I finally got the EDS diagnosis my Drs. agree to a hysterectomy that I had requested 3 or 4 years earlier. The day after the surgery I felt better than I had in years. I have not had another migraine since and I was a frequent flyer in my local ER. It’s been about 7 yrs since and I have had a bad 6 mos, but still am better at 52 than I was at 20 yrs.. though when I do get bad I go down quicker and stay down longer. My endocrine issues continue to plague me..but I’m on it! This site will make that adventure much easier!