Hi Momcat7, Boy, you give me WAY more credit than I deserve! It sounds like you, my friend, are the expert on this, not me! Having said that, I was right there with you on the familial trends of late-onset puberty, migraines, anxiety, etc. Yes — those are VERY typical in the EDS family. I believe, like you, that mast cell proliferation and lousy blood brain barriers are to blame for many of our issues.
Where I’m not sure I follow is the MSG thing. Are you saying that you believe MSG breaks down into L-glutamate (the excitotoxin in the brain)? IF that is your question, my answer is I don’t know! It’s an interesting thought, but as far as I know, there has only been anecdotal evidence of this. (Please correct me if I’m wrong). With our lousy BBB’s, mast cells and likely hydrocephalus, I don’t think we need to look further to find reasons for our symptoms — including tremors. But knowing that mast cell triggers involve some funky stuff, I could easily see how MSG may be a mast cell trigger and should be avoided.
That’s probably no answer (you get what you pay for. ha).Thanks for brainstorming! 🙂