I have had POTS since I was 22, about 23 years. I was diagnosed at Mayo Clinic and Vanderbilt after 3 to 4 years of trying to get a diagnosis. Without meds, my HR increases over 100 BPM with standing immediately and stays there until I sit down or lie down. My adrenaline levels standing are over 2000 without meds. I also had severe gastroparesis. I still have it but it is not as bad. I also have chemical sensitivities and I was exposed to chemicals and that was the trigger for the dysautonomia. I did test positive for mycoplasma early on but was never treated for it because my doctors felt the test was wrong. I believe it is a common co-infection for Lyme disease. I also have a severe mold allergy. I do plan on having allergy testing done again soon and getting tested again for the mycoplasma just in case it is still positive.