Beta Blockers didn’t work for me, they only made my peripheral circulation (and pain) worse.
I went down the non-pharmacological path regarding POTS treatment, when mine was diagnosed in 2004 i.e.
Raise the head of the bed (I was already sleeping sitting up at this point!)
Wear waist high support hose 24/7 (if not, then certainly thigh length hose)
Increased salt (a bacon sandwich a day helped ease the leg pains!)
Drink 2 litres of water per day (any more and you’re washing out essential minerals)
I can’t say it was a resounding success but it did help.
Barbara