Hi. I had the worst subluxation of my patella at 19. I progressed fast with more subluxations. I wound up with severe arthritis, degenerative joint disease, deformed legs, etc. I did every conservative treatment I could to by my self time, but I will say the last 9 years has been a down hill slide. I am now 37 with bilateral total knee replacements and I am disabled. I only found out this year that I had EDS. However, every person is different. Some are less affected by EDS than others. In my family of classical EDSers, I am the worst in the last two generations. I pray it stays that way. Shonda