Hi ScaredSingleMamainMaryland, Thanks for your responce. Could you tell me why a mass cell issue would cause the flushing? I dont think its allergy related because I dont have many allergies. I notice it happens sometimes when i get over stimulated(to much sound and light). however i dont know sometimes its just completely random. I do not take Zantac or Zyrtec. The yawning is horrible sometimes i do it so much that i have to hold my jaw in place because it will start to pop out due to streaching it so many times and my EDS. I dont know why I would have a lack of oxygen in my blood? however last time i was in the ER they had to check my lungs because my oxygen levels would keep dropping below 94. They ended up putting oxygen on me and taking the moniter off me because it kept going off. What is a vasovagal reaction? My cardiologist is getting aggravated because i have so many problems and she cant figure out how to fix me lol. My insomnia is getting worse and worse. I dont even know how im functioning right now to tell you the truth 2 hours of sleep in 3 days.Ugh. I also have tons of stomach issues and have lost 25 pounds with out trying in the last 3-4 weeks! because i cant eat with out running to the bathroom or throwing up. my doctor even had to go up on my beta blockers because all these symptoms were causeing my dysautonomia/POTS to flare up and i was passing out on a daily bases. Ugh I hope i feel better soon and find something to help!