I am taking 125 mg of diamox twice a day and taking 12-14 650 mg bicarb tablets a day. I just got labs back today that finally have my C02 in the normal range! First time in MONTHS! For some of us, it takes a LOT of bicarb to buffer the acidity from the diamox apparently.
I couldn’t handle being on propranolol… made me pass out. Just found out I actually do have hyper POTS, so different group of meds to treat that than “garden variety” POTS.
Hope that helps!