From what I remember and what I just read I don’t think that is exactly right. Here is a Q & A I found:
” Acetazolamide mechanism of action.?
Does anyone know the mechanism of diuresis caused by acetazolamide? I know it is a carbonic anhydrase inhibitor but how does this cause H+ retention and bicarbonate excretion?
Reply
The reaction of carbonic acid (H2CO3) to water and CO2 is catalized by carbonic anhydrase, but it’s inhibited by acetazolamide, which leaves carbonic acid which is unstable and becomes hydrogen ion (H+) and bicarbonate ion (HCO3). The H+ gets reabsorbed by the renal tubules and the bicarb is excreted in the urine.”
I believe because Diamox/Acetazolamide causes bicarb to be excreted in the urine is why bicarb is the base/buffer we are recommended to use.