Hmm, so I know close to nothing about mast cell disease, nor its relation to EDS, but from what I just read above, it seems Prednisone can aggravate these symptoms?
I’m wondering because I was given a round (two actually, but only took one full dose pack) of methylpred last summer for my severe lower back pain (early onset spinal arthritis) and it was around/after that time that my everything (MVP, joint pains, dysautonomia symptoms) began to really act back up like they haven’t in ten years… Interesting.