Oh, Richard — I forgot to mention that most of us have LVDD (article on my website), diagnosed with an echo. M.S. patients are also prone to developing this. One of my abstract publications was about how LVDD occurs (what chemicals were involved in tissue remodeling). I was looking for clues that could link the two conditions… I have LVDD, too, but it is likely NOT the cause of symptoms, but more of a red herring for the cardiologists. An AngII blocker is a decent medication to consider with your cardiologist. Narrow pulse pressure: many of us notice that, too. I know of one patient/friend whose latest BP reading at her doctor’s office was 90/90. Kid you not. Are the vessels becoming fibrotic? We don’t know. I will tell you that mine went back to normal, so I don’t *think* it’s fibrosis/sclerosis. I am curious if you ever flush? Have spider veins? Varicose veins in the family? Aneurisms in the family? When you have your echo, can you ask them to pretty please check the diameter of your inferior vena cava? Those can give us some clues… And FINALLY (promise), did you order your “23andme” genetic tests? You may want to consider doing that. We are opening the discussion to our genetic defects, and I believe these will guide us toward answers, I really do. Keep the faith, my friend. I got about as bad as one can get with this condition, yet am now thriving. It wasn’t easy, but problems I thought were permanent, I was able to correct/heal/recover. You’ll get there… 🙂