Please check with your doc, but I looked at my serum B12 levels to start. Now I just inject some once in a while, and take a lozenge under my tongue a couple times a week. Although I’ve never heard of someone’s level being too high, I did research to be sure I could be a bit sloppy with it, and found that it is almost impossible to overdose on it (lucky for me!). As far as HGH goes, I’ve taken a lot of different forms — I’m on Omnitrope right now. They are all very pricey — about $400/month and you inject it subQ. Research is scanty, but at least one study showed that it helped pain of fibromyalgia. I initially started it just to try to maintain some muscle mass during menopause (which didn’t happen, BTW!). Now I see that it does seem to help with pain, and that was one reason I never had pain before! I thought I was just lucky. ha. Your doctor will help you figure out your initial dose, then retest. I inject it 5-6 days/week. They still think it is a good idea to take a day off during the week to maintain the feedback loop (so your body doesn’t stop making its own). I really can’t tell you if it is worth the cost, though, honestly. All of us seem to have “endocrinology gone wild” and it is TOUGH to get things stable. FOR SURE!