What helps me since I have very low blood pressure (may not be safe if you have high BP) is when I am really down and depressed I dive down to the bottom of the pool and hang out for a bit. Somehow I knew this would kick out the depression and it does almost immediately. Later I learned this triggers the “dive reflex” that we share with penguins and other animals. It slows the heart rate, vasoconstricts which increases arterial blood pressure! The purpose of these combined reflexes is to conserve oxygen and to redirect blood to the brain and heart. I had also learned that cold water showers a couple of times a day is great for depression and has many other benefits. If there was a fire and I had to grab 2 of my supplements it would be the Butcher’s Broom and Licorice. Anything that constricts makes me feel a lot better physically and emotionally.