I have read some where that persons with EDS can rapidly metabolize some things like anesthesia, but slower on other things. I also read that there is a gene that can be tested for to tell you where you fall on metabolizing things. I think with all our issues our liver, small bowl, etc don’t work as well as a healthy person. I personally have trouble absorbing vitamins, iron, calcium, etc., but I rapidly metabolized anesthesia and painkillers. I know it takes a long time to rid your body of heavy metals because your liver and spleen have to clean out all the red blood cells that are poisoned by the metals. Your body replaces only 1% of its red blood cells each day. Therefore, it will take over 100 days to replace all your red blood cells. Also, if your bone marrow is also affected it will take even longer to rid your body of the heavy metals. The bone marrow is where all your red blood cells come from. I also, remember a study that showed that women that intend to get pregnant should avoid fish that contain high levels of mercury for a year prior to becoming pregnant because the mercury stays in your system that long