We have neck misalignments because our ligaments are too loose. Ligaments are there to hold bones together in a certain way. Doesn’t always work that way with us as the ligaments get more and more lax.
C1/C2 misalignments can have varied effects. C1/C2 is still considered part of the brain stem so you can imagine the implications.
Traditional chiro adjustments are too fast, too much torgue, and will only make our ligaments and tendons more lax. IF you can find a good PT or chiro who TRULY understands connective tissue disorders then they can be very helpful. My PT is a God sent, but while I got temporary relief from the chiro I am pretty sure he made my neck MUCH worse, including craniocervical misalignment and increasing laxity of ligaments.
Zoloft was ok for me. Cymbalta was a nightmare. My PCP and I can’t remember exactly what it was, but I was way “off” when on it and we quickly pulled me off it.
As for unusual reactions…. get used to it. We are wired differently. Very differently. Our bodies metabolize meds differently, deal with pain differently, etc. Even amongst bendies how we react is varied. Collagen is one of the main building blocks of our body so when it goes wrong the potential for bad things to happen is pretty good.