Hello, my friend. I hate to hear that you are dealing with this. 🙁 If you have a CTD, I understand your concern about the LP — been there! If you and your doctors can figure this out noninvasively, I’d be all for it! You know to watch your CO2 levels, right? The magic number is 22 or above to keep Diamox working well. You are right that spinal leaks causing low ICP are relieved when lying down. Sometimes symptoms of high ICP mimic those of low ICP. Instead, we can sometimes look for hints in the MRI’s, fundus exams, and — you guessed it — response to treatment. Hang in….