I’m so sorry you are dealing with this with a young child. 🙁 I know how hard that can be… Can I just throw out a couple of things? A B12 deficiency can mimic M.S., so it’s always good to rule that out! Your doctor will want a serum B12 (which may be normal), an MMA, a homocysteine, and a Holo-TC to know for sure. It sounds like she’s had imaging. Any dural ectasia? Any signs of demyelination on the brain MRI? (did she have a brain MRI?) A good allergist/immunologist is a great idea, as is a complete team (I know — that’s a tough one!). Oh, BTW, if in doubt, you can buy strips for urine that will tell you if she is having a UTI or not. Believe it or not, for a while, I was having chronic UTI’s AND vaginal yeast infections, and I was hurting so much, I couldn’t tell what the pain was from! Antibiotics can make a yeast infection worse — I didn’t want to take them “just in case”. The strips helped me figure it out and may be very valuable for use for kids.