I have found relief from nausea that i have suffered with for many years from mast cell treatment. Benadryl is helping at last! Another one of the hundreds that i did try was called Resolor and it speeds up motility mostly in the lower bowel, but can help upper GI problems too. It did help slightly. I am also looking at options next month for a gastric pace maker, but i am trying Dr Driscolls meds before i commit to anything that drastic, although drastic measures are needed!