Hi Lab-Scientist-Lady!
My great grandfather and great uncle actually lost their eye. The orbit ruptured. In my never ending research today, I found EDS VI (kyphoscoliosis type) that has been known to have orbit ruptures. It is extremely rare though. I don’t have much medical information about my great grandfather, but I do have a small amount on my great uncle believe it or not. It is a physician evaluation of my great uncle and my grandfather when they entered an orphanage around 1909-1911. The medical terminology is different than today and I would need to research it out. Maybe it would provide some clues.
I have an appointment with a geneticist in March 2014. It is such a long ways away…