I don’t know that it skips generations but it shows up differently in each generation. I do not have the severity that my son has, although I have had my esophagus ruptured and knee surgery twice-my grandma died of a aneurysm and my uncles have all had their stomachs ruptured, on that same side. But no one is as hypermobile as my son, not even me and I’m pretty hypermobile. We would have never connected it to one thing though. The Dr at Shriners we just saw said the same exact thing: it’s just different in everyone-especially if you hadn’t heard of it before, you don’t look for the connections.