I have ridges in my nails going virticle. When i turned in a coupon to get a free manicure the women commented asking me if i was sick. Interestingly you talk about MCA. i have had high tryptase results 3 times and twice they have been just at normal range. My endo says she thinks i have mca. but since it is not giving me problems not to worry. She did send me to a hemotologist. Who ran the test. And told me if it comes back high he will perform a bone marrow biopsy. So i assume it came back normal as has never contacted me. i Also am very deficent in my vit D b-10 they also have me on q-10 and l-carnitine as those levels off aswell. a prior backround i am diagnosed with EDS hypermobility, Pots, small fiber neuropathy, pseudotumor ceribri and a minor 3 to 4mm chiari. I find your articles very interesting. esp because everything you talk about i have been diagnosed with! lol Ty Dr Diana for your wonderful site!