This is really tough, Barb! I used to love wine with dinner and had to give it up, also. 🙁 It’s my hunch that it causes enough vasodilation to make it not worth it! I threw caution to the wind one evening, though, and had two drinks one evening. They were espresso based, so I thought the caffeine would off-set the vasodilation and I would be OK. The next day I had nystagmus in the morning! I knew then that alcohol was doing more than just dilating my already defunct vessels! Yikes. I watched the video and am VERY familiar with our endothelial research. Absolutely, more research needs to be done about our vasculature. After I had the procedure discussed in the video, I had no improvement, but I did develop a huge thrombosis (blood clot) in that vessel. I was put on Heparin and developed osteoporesis from Heparin. My gut is telling me that folks with connective tissue disorders and weak vessels are prone to vessel and endothelial damage from many things — including this procedure, but we are also prone to blockages of the veins (due to thrombosis and other causes) making this a very “catch 22” situation. I know some doctors who are working on a procedure to try to break through venous clots, but they have not moved beyond a patent yet. So today, we work on vessel health, blood thinning as needed and prevention of fibrosis when appropriate. Do you know if the vessels leading to your liver are OK? Makes you wonder, doesn’t it? 😉