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Can a person have mast cell disease but biopsoies both from esophagus to stomach, small intestine and colon nad some large intestine be normal showing no inflaamatory process, and all tests for autoimmune all normal? There have been no skin biopsies performed.
Can Mast cell disease show up in genetic testing?
Hi again — yes, you can have mast cell with negative biopsies — mast cells can hide in various tissues and organs. And no, I don’t believe there is a genetic test for MCAD. The docs like to get a bone marrow biopsy, because that is where mast cells are “born”. But even those results are not a guarantee either way. There is a big push to just TREAT it, because they think the current criteria is missing over half of us. Yikes.