NEW STUDY! Parasym Plus™ for Multiple Sclerosis › Forums › PrettyIll.com Discussion › Skin › I see most have POTS in this forum-Does autonomic neuropathy qualify? › Reply To: I see most have POTS in this forum-Does autonomic neuropathy qualify?
I would definitely think it applies. The authors of this medscape paper say POTS patients seem to suffer from a type of autonomic neuropathy. http://www.medscape.com/viewarticle/717904_5
“These patients seem to suffer from a mild type of autonomic neuropathy; the peripheral vessels cannot constrict when there is orthostatic stress. In many patients symptoms start abruptly following viral infections, trauma, surgery and after pregnancy. Serum auto-antibodies to alpha-3-acetylcholine receptors of the peripheral ganglia have been detected in some patients with a post-viral presentation. In some cases, there is a hyperadrenergic state leading to increased noradrenaline due to impaired clearance or decreased uptake of noradrenaline by the synaptic cleft. These patients suffer from profuse sweating, anxiety, tremulousness, tachycardia and high blood pressure. This variety usually runs in families and is thought to be due to an underlying genetic disorder. The secondary form of the disorder is seen in conditions associated with autonomic neuropathy, e.g. diabetes mellitus or amyloidosis, and in conditions that may be associated with intrinsic abnormalities in capacitance vessels, e.g. hypermobility syndromes. In other conditions the underlying pathogenesis is less clear, e.g. Sjögren’s syndrome.”