Hi Tareq, I would absolutely encourage your doctors to help you with a trial of Diamox and a brain MRI. To date, every person we’ve seen with even a small Chiari at POTS Care, has experienced some dramatic improvements with Diamox (even elimination of the Chiari in a couple of cases). Quite a few patients were able to avoid neck fusions, too. The next step is to focus on what has made the intracranial pressure increase. If you are like many of us, there are often underlying causes of the increase in pressure that tie in with chronic fatigue. It can be tough to figure out, but absolutely worth it! Meanwhile, Diamox can significantly improve your quality of life, if you are affected by high pressure. Hang in, my friend.