Hi Tareq, Diamox does wonders for the sort of listless fatigue I have always had. Not so much for the physical kind, where I get winded going up stairs, or for the sleepy kind associated with my narcolepsy. (Which I treat with low-dose naltrexone and Xyrem, respectively).
By listlessness, I mean that I just don’t have the urge to do anything. I feel confused, bored, maybe a little depressed. Almost always accompanied by extreme cold sensitivity–like the cold is burning my skin.