Hi. From what I understand reduced NO increases mast cell activity…
Welcome to the “family”! 🙂
I wish someone could clear this up for me! I have grappled with this for quite a while.
Here’s a great article:http://www.ncbi.nlm.nih.gov/pubmed/18285401
It describes how NO can prevent mast cells from activating (sounds good), and allows them to survive longer (not so good). Mast cells are not all bad, of course, but if we have too many, and/or they’re too sensitive, would it be best to have more of them if they’re less reactive? Hmm… I think the jury is still out on that…