Hi, thank you for your response, I have read up about Diamox and how to maintain good levels for it to be effective, I want to do all I can to ensure it does the job, I’m taking no chsnces. I am looking into bicarb tablets or alkaline drops for water and obviously eating as alkaline as possible. I already take potassium supplements and eat my fair share of bananas, I tend to steer clear of analgesics on the whole but good to know to not take asprin in any case. I’m just unsure of PoTS meds, whether beta blockers, alpha antagonists or medications that increase blood volume should be avoided with Diamox. I’m sure everyone here know how confusing this can all be.