Thanks, Dr. Diana! I missed the facebook discussion so I’ll check that out. I did see your video. I’m so glad you and your kids don’t have any methylation pathway mutations… I had twelve and two are homozygous! I know it is NOT the end all be all…. just part of the puzzle for me. I know the answer isn’t down any one rabbit trail and having spoken to you on the phone… I know you are going to have more answers for us soon. Blessings to you and yours this holiday season! Big Hugs! SweetFeather