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Hello everybody. I’ve been visiting this site on and off for probably a year or two and I love all the information I’ve been gathering. I have many questions that I’d love to post but my current inquiry is regarding mast cells.
I’m very curious about the connection between mast cells and fevers. I have seen fever listed as a possible symptom of mast cell conditions but it’s always listed in passing with no details given. I’m wondering if any of the substances released when mast cells degranulate induce fever. I know some types of prostaglandins have a pyrogenic effect but I’m finding it difficult to learn which types are released by the mast cells and which types elevate temperature vs decrease it. If anyone has any knowledge about how a fever can be caused by mast cells I’d love to hear it.
I haven’t read any complaints from MCAS patients regarding fevers, what type of fevers could this cause? Would it be a constant low grade fever or could it be a sporadic thing that could be mistaken for a virus. Perhaps mast cell related ‘episodes’ could cause an elevated temperature that would mimic some common illnesses with symptoms of fever, body aches, headache etc.?
If anyone has any insight here or experience with these things please share your thoughts. I’d love to figure out if the MCAS~fever connection is pertinent to me. I don’t think it is, but I just want to cover all bases.
Thanks so much guys.~Anna
Ps: I guess it would make sense to ask if anyone knows of any other connection between EDS (esp. hypermobile type) and fevers. I’ve done some googling and found the following article but overall I’m just not finding much.
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