NEW STUDY! Parasym Plusโข for Multiple Sclerosis › Forums › PrettyIll.com Discussion › The Latest Research › hiGH B12 ANYONE? HYPERADRENERGIC POTS Dr. Diana pls help I am newbie
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monia akhis.
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November 20, 2013 at 4:51 pm #4612
charlie1
ParticipantDr. Diana, Sorry to hear that you are going through such a frustrating time with the muscle wasting. Having a diagnosis would make things so much easier when we try to deal with our illnesses(both for our sanity and obviously for treatment). I agree that trying out the easy stuff, working on B12 deficiencies if that’s in order, is a better way to start then venturing down the tricky path of eosinophilic disorders.
Regarding B12 testing, glad to hear that Quest has added Holo-TC to their blood test list. I’m hoping that it is offered here in Canada as well. Too bad that Quest doesn’t also offer the MMA testing (either urine or blood) but I suppose it’s cost prohibitive.
I found this short concise explanation (in comparison to the lengthy, in-depth explanations often found) of Active B12 for anyone interested –
One of the biggest problems with diagnosing B12 deficiency is that the conventional serum B12 test that most doctors run only picks up a small fraction of people who are actually B12 deficient. This test measures the total amount of B12 in the blood, and does not rule out functional B12 deficiency. (1) More sensitive markers for B12 deficiency are now available, including methylmalonic acid (MMA) and holotranscobalamin II (holo-TC). MMA is converted to succinic acid via an active-B12 dependent enzyme, so if MMA levels are high, it suggests that active B12 is lacking. Holotranscobalamin II is composed of vitamin B12 attached to transcobalamin, and it represents the biologically active part of B12 that can actually be delivered to the cells and perform all of the functions of B12. Studies using these newer methods report much higher levels of deficiency than studies using only serum B12.
November 20, 2013 at 4:59 pm #4613ourfullhouse
ParticipantAnd please don’t forget that B12 should be given in the muscle, not “subQ”. (Yes, I made that mistake for a while! ๐
Dr. Diana, can you explain why B12 should be in the muscle instead of subQ? I have been having mine subQ for a couple of years no! **sigh** That is how my ND said to do them. :shut:
Hate the thought that it could have been doing more good/made me feel better if it was injected into the muscle all this time! Boo.
November 22, 2013 at 5:53 pm #4615Barbara
ParticipantAnd please don’t forget that B12 should be given in the muscle, not “subQ”. (Yes, I made that mistake for a while! ๐
Dr. Diana, can you explain why B12 should be in the muscle instead of subQ? I have been having mine subQ for a couple of years no! **sigh** That is how my ND said to do them. :shut:
Hate the thought that it could have been doing more good/made me feel better if it was injected into the muscle all this time! Boo.
Me too, I’ve been injecting B12 into the fat over my stomach.
November 22, 2013 at 8:33 pm #4618Dr. Diana
KeymasterThat is awesome information Charlie1! I should’ve been more clear, though. Quest does offer MMA urine and blood testing. Yay! Although I went ahead and started on B-12 shots because I woke up the next day and my feet were tingling, I may still run all of the tests. That would be a serum B12, homocysteine, MMA and Holo-TC. I feel a video coming on! I scoped out various forums, and found a plethora of folks with high B-12 yet indicating B-12 deficiencies. It was enough to convince me that it was worth a try. So far, so good. My tingling has stopped in my hands and feet. Was it related to the B-12? We may never know. ๐
November 22, 2013 at 8:36 pm #4619Dr. Diana
KeymasterAnd please don’t forget that B12 should be given in the muscle, not “subQ”. (Yes, I made that mistake for a while! ๐
Dr. Diana, can you explain why B12 should be in the muscle instead of subQ? I have been having mine subQ for a couple of years no! **sigh**
Sure, it’s because that’s what they said we need to do! ๐ I’m sure we could Google for the scientific reason, and when things slow down, I’ll look it up! Meanwhile, just understand that it needs to be in the muscle. I’m just glad to know I wasn’t the only one! ๐
November 22, 2013 at 8:41 pm #4620Dr. Diana
KeymasterMe too, I’ve been injecting B12 into the fat over my stomach.
Oh no, you two, Barb! Well it’s a good thing we’ve had this chat! ๐ It’s also good that I’m sure you have no fat on your stomach. I’m sure it went straight into your six pack muscle. (Isn’t the Internet wonderful?) ๐
November 24, 2013 at 7:13 pm #4623Barbara
ParticipantMe too, I’ve been injecting B12 into the fat over my stomach.
Oh no, you two, Barb! Well it’s a good thing we’ve had this chat! ๐ It’s also good that I’m sure you have no fat on your stomach. I’m sure it went straight into your six pack muscle. (Isn’t the Internet wonderful?) ๐
Six pack, LOL!! on the contrary because I am growth hormone difficient, the fat that I have stored is mainly over my stomach and belly – but hopefully the growth hormone injections will resolve that (along with the poor memory, the muscle weakness, the endurance issues, etc) – I can but hope.
Empty sella = flattened pituitary = all sorts of hormone problems!
Barbara
(UK)November 24, 2013 at 11:30 pm #4625sixboots
ParticipantI just got lab results back (via a patient portal) and will be seeing my doctor on Tuesday. My vitamin b 12 was greater than 2,000. I have always felt better when I took b12 sub lingual but I haven’t taken it for at least a couple of months. I would like to gather as much info as I can about a possible vitamin b12 deficiency vs. very high levels. I am pretty concerned what this dr will say as she is a new dr. for me. I also might add that my vitamin d was pretty low at 19 (values 30-150). I have been searching the net an haven’t found any real reliable information. I did watch the video that was posted (most of it before I got kicked off for some reason).
Would love to have more info on this.
Shellie
November 25, 2013 at 10:43 pm #4627ourfullhouse
ParticipantAnd please don’t forget that B12 should be given in the muscle, not “subQ”. (Yes, I made that mistake for a while! ๐
Dr. Diana, can you explain why B12 should be in the muscle instead of subQ? I have been having mine subQ for a couple of years no! **sigh**
Sure, it’s because that’s what they said we need to do! ๐ I’m sure we could Google for the scientific reason, and when things slow down, I’ll look it up! Meanwhile, just understand that it needs to be in the muscle. I’m just glad to know I wasn’t the only one! ๐
Dr. Diana,
I checked with my naturopath and he is unaware of any scientific information as to muscle absorption of B12 being much different than subQ and so would greatly appreciate if you have a study, paper, etc. to back that up that he can look at. His inquiry into the subject showed that B12 is absorbed just fine subQ and IM is so much more painful that it would have to be a significant enough difference to make IM worthwhile. :ohh:November 29, 2013 at 3:45 am #4631monia akhis
ParticipantPrecio endodoncia o tratamiento de conductos los molestos dolores de diente que nos impiden realiza nuestras actividades diarias. Valoraciรณn Gratis.
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